一种牛病毒性腹泻疫苗的评估
Evaluation of a bovine virus diarrhea vaccine.
作者信息
Chapek M L, McClaughry L E, Wilkins L M
出版信息
Mod Vet Pract. 1978 Oct;59(10):755-7.
Singer Strain bovine virus diarrhea (BVD) modified live-virus vaccine, produced in a continuous bovine cell line using equine serum in the growth medium, evoked a high level of serum antibodies and protected against virulent challenge in vaccinated calves. Transmission of vaccinal virus from vaccinated cattle to susceptible controls did not occur when vaccinated and nonvaccinated cattle were kept in constant contact for 23 days. Postvaccinal reactions to the viral vaccine were not observed in vaccinated cattle from 10 feedlots or in cattle vaccinated with multiple doses of the experimental vaccine.
歌手株牛病毒性腹泻（BVD）减毒活疫苗，在连续牛细胞系中使用生长培养基中的马血清生产，在接种疫苗的犊牛中引发了高水平的血清抗体，并能抵御强毒攻击。当接种疫苗的牛和未接种疫苗的牛持续接触23天时，疫苗病毒并未从接种牛传播至易感对照牛。在10个饲养场的接种牛或接种多剂实验疫苗的牛中均未观察到对该病毒疫苗的接种后反应。
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