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[戊巴比妥对移植到大鼠脑内的胚胎神经组织细胞脉冲序列的影响]

[The effect of nembutal on the cellular pulse trains of embryonic nerve tissue transplanted into the brain of the rat].

作者信息

Senatorov V V, Obukhova G P, Silakov V L

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1990 May-Jun;40(3):550-7.

PMID:2169162
Abstract

Under nembutal anaesthesia the mean frequency of single unit discharges recorded from allografts of the rat brain was four times lower than the one measured in unanaesthetized animals. A diminished variability was revealed of firing rates and discharge patterns of the cells within grafts in anaesthetized rat brain. In comparison to unanaesthetized animals the number of graft units reacting to a tactile stimulation of contralateral hindlimb of the operated animals was twice lower. Nembutal anaesthesia provoked a full blockade of reactions to the tactile stimuli applied to the ipsilateral side of the animal body.

摘要

在戊巴比妥麻醉下,从大鼠脑同种异体移植物记录的单个单位放电的平均频率比未麻醉动物中测量的频率低四倍。在麻醉的大鼠脑中,移植物内细胞的放电率和放电模式的变异性降低。与未麻醉的动物相比,对手术动物对侧后肢进行触觉刺激有反应的移植物单位数量减少了一半。戊巴比妥麻醉导致对施加于动物身体同侧的触觉刺激的反应完全受阻。

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