National Research Centre for the Working Environment, Copenhagen, Denmark.
Int Arch Occup Environ Health. 2012 Apr;85(3):305-10. doi: 10.1007/s00420-011-0668-x. Epub 2011 Jun 22.
The relationship between occupational physical activity (OPA) and mortality has mainly been studied among males and shows conflicting results. This study examines this relationship in a cohort of both male and female workers.
OPA was determined by 4 self-reported questions in a representative sample of 5,839 Danish workers aged 18-59 years at baseline. A 19-year follow-up on mortality was assessed by linkage with the national death registry. Gender-stratified Cox regression models were used to determine the effect of high OPA on all-cause mortality while controlling for age, BMI, smoking, alcohol consumption, doctor-diagnosed disease, influence at work, and social class.
Two hundred and sixty-two males (8.6%) and 174 females (6.2%) died during follow-up. Being in the highest quartile of OPA predicted an increased risk for all-cause mortality among male workers (HR: 1.79, CI: 1.19-2.70), but not among female workers (HR: 0.99, CI: 0.65-1.49) compared with workers in the lowest quartile of OPA. Among females, indications of a u-shaped relationship between occupational physical activity and all-cause mortality were found.
The findings indicate that high occupational physical activity increases the risk for all-cause mortality among male workers. Future studies need to further examine gender differences in the effects of OPA on mortality.
职业体力活动(OPA)与死亡率之间的关系主要在男性中进行了研究,结果存在矛盾。本研究在男性和女性工人队列中研究了这种关系。
在基线时,通过对 5839 名丹麦 18-59 岁工人的代表性样本进行的 4 个自我报告问题来确定 OPA。通过与国家死亡登记处的链接,评估了 19 年的死亡率随访。性别分层的 Cox 回归模型用于确定高 OPA 对全因死亡率的影响,同时控制年龄、BMI、吸烟、饮酒、医生诊断的疾病、工作影响和社会阶层。
在随访期间,有 262 名男性(8.6%)和 174 名女性(6.2%)死亡。与 OPA 最低四分位数的工人相比,处于 OPA 最高四分位数的男性工人全因死亡率的风险增加(HR:1.79,CI:1.19-2.70),但女性工人则不然(HR:0.99,CI:0.65-1.49)。在女性中,发现职业体力活动与全因死亡率之间存在 U 型关系的迹象。
这些发现表明,高职业体力活动会增加男性工人全因死亡率的风险。未来的研究需要进一步研究 OPA 对死亡率的影响在性别方面的差异。