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人体因粪便失禁行硅胶注射后发生局部巨大细胞异物反应：两例报告。

Local giant cell foreign body reaction after silicone injection for fecal incontinence in humans: two case reports.

机构信息

Department of Surgery, Maastricht University Medical Centre, P. Debyelaan 25, 6202 AZ, Maastricht, The Netherlands.

出版信息

Tech Coloproctol. 2012 Oct;16(5):395-7. doi: 10.1007/s10151-011-0702-8. Epub 2011 Jun 22.

DOI:10.1007/s10151-011-0702-8
PMID:21695441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3444698/
Abstract

Since the 1990s, one of the methods used for treating fecal incontinence due to internal anal sphincter defects has been the injection of bulking agents. The aim of this paper is to report two cases of local giant cell foreign body reaction after injection of PTQ(TM) in humans. To the best of the authors' knowledge, this is the first report of an adverse immune response to silicone injection in humans.

摘要

自 20 世纪 90 年代以来，治疗因内部肛门括约肌缺陷导致的粪便失禁的方法之一是注射填充剂。本文旨在报告两例人类注射 PTQ（TM）后发生局部巨细胞异物反应的病例。据作者所知，这是首例报道的人类硅酮注射免疫不良反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d125/3444698/47d69fe1eb56/10151_2011_702_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d125/3444698/968957029781/10151_2011_702_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d125/3444698/47d69fe1eb56/10151_2011_702_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d125/3444698/968957029781/10151_2011_702_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d125/3444698/47d69fe1eb56/10151_2011_702_Fig2_HTML.jpg

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2
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Systematic review on the efficacy and safety of injectable bulking agents for passive faecal incontinence.
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Colorectal Dis. 2010 Apr;12(4):296-303. doi: 10.1111/j.1463-1318.2009.01828.x. Epub 2009 Mar 6.
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