The Department of Orthopaedics, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
J Surg Oncol. 2011 Nov 1;104(6):561-5. doi: 10.1002/jso.22003. Epub 2011 Jun 21.
Functional outcomes following oncologic total femoral endoprosthetic reconstruction (TFR) are lacking. We compared patient-oriented functional results of TFRs to proximal femur and distal femur reconstructions (PFR and DFR). We also compared function and complications with regard to knee and hip componentry.
Fifty-four TFR patients were identified from three institutional prospective databases. Forty-one had fixed- and 13 had rotating-hinge knees, 37 hemiarthroplasty and 17 total hip arthroplasty componentry. Toronto Extremity Salvage Scores (TESS) for n = 27 were compared between groups and to cohorts of PFR (n = 31) and DFR (n = 85) patients using the Mann-Whitney U-test.
Follow-up averaged 4 years. Mechanical complications included five hip dislocations and one femoral malrotation. Four dislocations were in fixed-hinge implants, all in those lacking abductor reattachment. TESS averaged 69.3 ± 17.8, statistically decreased from DFR (P = 0.002) and PFR patients (P = 0.036). No significant differences were detected between patients in the fixed-hinge (n = 18) and rotating-hinge (n = 9) groups (P = 0.944), or total hip (n = 8) and hemiarthroplasty (n = 19) groups (P = 0.633).
TFR is reserved for extreme cases of limb salvage, portending a poor prognosis overall. Function reflects additive impairments from PFR and DFR. TFR outcomes differ little with rotating- or fixed-hinge, total hip or hemiarthroplasty implants.
目前缺乏关于全股骨肿瘤假体重建(TFR)后功能预后的相关研究。本研究比较了 TFR 与股骨近端重建(PFR)和股骨远端重建(DFR)患者的面向患者的功能结果。我们还比较了膝关节和髋关节假体的功能和并发症。
从三个机构前瞻性数据库中确定了 54 例 TFR 患者。41 例患者采用固定铰链膝关节,13 例采用旋转铰链膝关节,37 例采用半髋关节置换,17 例采用全髋关节置换。使用 Mann-Whitney U 检验,将 27 例 TESS 评分与 PFR(n=31)和 DFR(n=85)患者的评分进行比较。
平均随访 4 年。机械并发症包括 5 例髋关节脱位和 1 例股骨旋转不良。4 例脱位发生在固定铰链假体中,均在未行外展肌重建的患者中发生。TESS 平均为 69.3±17.8,与 DFR(P=0.002)和 PFR 患者(P=0.036)相比显著降低。在固定铰链(n=18)和旋转铰链(n=9)组(P=0.944)或全髋关节(n=8)和半髋关节(n=19)组(P=0.633)之间未检测到患者之间的显著差异。
TFR 适用于肢体挽救的极端病例,总体预后较差。功能反映了 PFR 和 DFR 的附加损伤。TFR 结果与旋转或固定铰链、全髋关节或半髋关节假体的结果差异不大。