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在股骨近端大假体重建中,与仅进行软组织外展肌修复相比,大转子的骨性重新附着是否必要?

Is osseous reattachment of the greater trochanter necessary compared to soft-tissue-only abductor repair in proximal femoral megaprosthesis reconstruction?

作者信息

Groundland John, Brown Jeffrey, Jones Kevin, Randall R Lor

机构信息

Sarcoma Service, Department of Orthopedics, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.

Department of Orthopedics, University of Miami Miller School of Medicine, Miami, Florida, USA.

出版信息

J Surg Oncol. 2021 Jul;124(1):115-123. doi: 10.1002/jso.26477. Epub 2021 Mar 25.

Abstract

BACKGROUND

One of the challenges to surgical reconstruction following oncologic proximal femur resection is reliable re-establishment of the abductor mechanism. Surgical and functional outcomes following re-approximation of the abductor mechanism to a metallic endoprosthetic after tumor resection of the proximal femur have not been well established in the literature.

METHODS

A retrospective review was performed, inclusive of patients who received a proximal femur replacement with a metallic endoprosthesis following tumor resection. Patients were divided into two groups: (1) those that received an abductor repair involving a trochanteric osteotomy and osseous fixation of the greater trochanter/abductor mechanism to the endoprosthesis, and (2) those that did not have a trochanteric osteotomy and therefore had an abductor repair consisting of only soft tissue reattachment to the endoprosthesis. The two groups were assessed for demographic characteristics, diagnosis, surgical outcomes including rates of complication and failure, radiographic evidence of trochanteric failure, and functional outcomes. Descriptive statistics, comparative statistics, and logistic regression analyses were performed to discern differences between the two study groups.

RESULTS

Fifty-three patients were included in the analysis, 29 had abductor reconstructions involving reattachment of the greater trochanter to the metallic endoprosthesis and 24 had soft tissue reconstruction of the abductor mechanism without bony fixation. There were no differences between the two groups for demographic data, cancer diagnosis, follow up, or survivorship. Radiographic evidence of trochanteric dissociation from the endoprosthesis was observed in 45% of osteotomy cases. Only 10% of patients in the trochanter osteotomy group and 38% of the soft tissue only group were able to resume a normal, non-Trendelenburg gait at final postoperative visit (p = .024). Need for an assistive ambulatory device was seen in 83% and 67% of the osteotomy and soft-tissue-only patients, respectively (p = .21).

CONCLUSION

Re-establishing the abductor mechanism following proximal femur oncologic resection remains a challenge to orthopedic oncologists. Even when possible, salvage of the greater trochanter for reattachment to the endoprosthesis did not lead to improved function in this series, when compared to a similar cohort that received a soft-tissue-only abductor repair. Abductor mechanism reconstruction with a greater trochanteric osteotomy and subsequent fixation to the proximal femur endoprosthesis had a high rate of radiographic failure. Additionally, reattachment of the greater trochanter to the proximal femur endoprosthesis demonstrated no improvement in Trendelenburg gait or reliance on an assistive ambulatory device when compared to a soft-tissue-only abductor repair.

摘要

背景

肿瘤性近端股骨切除术后外科重建面临的挑战之一是可靠地重建外展肌机制。在近端股骨肿瘤切除后,将外展肌机制重新附着于金属内假体后的手术和功能结果在文献中尚未得到充分证实。

方法

进行了一项回顾性研究,纳入了肿瘤切除后接受金属内假体近端股骨置换的患者。患者分为两组:(1)接受涉及转子截骨术并将大转子/外展肌机制骨固定于内假体的外展肌修复的患者,(2)未进行转子截骨术,因此外展肌修复仅包括将软组织重新附着于内假体的患者。评估两组的人口统计学特征、诊断、手术结果,包括并发症和失败率、转子失败的影像学证据以及功能结果。进行描述性统计、比较统计和逻辑回归分析以辨别两个研究组之间的差异。

结果

53例患者纳入分析,29例进行了将大转子重新附着于金属内假体的外展肌重建,24例进行了外展肌机制的软组织重建且无骨固定。两组在人口统计学数据、癌症诊断、随访或生存率方面无差异。在45%的截骨病例中观察到转子与内假体分离的影像学证据。在术后最后一次随访时,转子截骨术组仅10%的患者和仅软组织组38%的患者能够恢复正常的、无Trendelenburg步态(p = 0.024)。分别有83%的截骨术患者和67%的仅软组织患者需要辅助行走装置(p = 0.21)。

结论

近端股骨肿瘤切除后重建外展肌机制仍然是骨肿瘤学家面临的挑战。即使有可能,在本系列中,与接受仅软组织外展肌修复的类似队列相比,保留大转子以重新附着于内假体并未导致功能改善。采用大转子截骨术并随后固定于近端股骨内假体的外展肌机制重建有较高的影像学失败率。此外,与仅软组织外展肌修复相比,将大转子重新附着于近端股骨内假体在Trendelenburg步态或对辅助行走装置的依赖方面未显示出改善。

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