Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects.
作者信息
Kohi F, Miyagawa H, Agrawal D K, Bewtra A K, Townley R G
机构信息
Allergic Disease Center, Creighton University, Omaha, NE.
出版信息
Ann Allergy. 1990 Sep;65(3):228-32.
PMID:2169715
Abstract
We determined the relationship of allergic disease to the number and activity of eosinophils and their production of leukotriene B4 and leukotriene C4 (leukotriene D4 equivalents). Granulocytes from allergic rhinitis (AR) subjects and asthmatics release more LTC4 than normals. Furthermore, eosinophils of asthmatics generate more LTC4 than those of AR subjects.
摘要
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