Paithankar Karthik S, Sørensen Henning O, Wright Jonathan P, Schmidt Søren, Poulsen Henning F, Garman Elspeth F
Laboratory of Molecular Biophysics, Department of Biochemistry, University of Oxford, South Parks Road, England.
Acta Crystallogr D Biol Crystallogr. 2011 Jul;67(Pt 7):608-18. doi: 10.1107/S0907444911015617. Epub 2011 Jun 16.
The potential in macromolecular crystallography for using multiple crystals to collect X-ray diffraction data simultaneously from assemblies of up to seven crystals is explored. The basic features of the algorithms used to extract data and their practical implementation are described. The procedure could be useful both in relation to diffraction data obtained from intergrown crystals and to alleviate the problem of rapid diffraction decay arising from the effects of radiation damage.
探讨了在大分子晶体学中利用多个晶体同时从多达七个晶体的集合中收集X射线衍射数据的潜力。描述了用于提取数据的算法的基本特征及其实际实现。该方法对于从共生晶体获得的衍射数据以及缓解由辐射损伤效应引起的快速衍射衰减问题都可能有用。