色素上皮衍生因子：胰岛素抵抗的非交感调节因子？
Pigment epithelium-derived factor: a not so sympathetic regulator of insulin resistance?
机构信息
Department of Health and Exercise Science, Colorado State University, Fort Collins, CO 80523-1582, USA.
出版信息
Exerc Sport Sci Rev. 2011 Oct;39(4):187-90. doi: 10.1097/JES.0b013e31822673f0.
Pigment epithelium-derived factor (PEDF), an adipokine, is a regulator of oxidative stress, inflammation, angiogenesis, and insulin sensitivity. Contrary to animal and cell culture data, inhibition of the sympathoadrenal system does not affect serum PEDF in humans. However, during acute beta-adrenergic receptor stimulation serum PEDF concentration is decreased. PEDF may be involved in cross talk between adipose tissue and skeletal muscle.
色素上皮衍生因子（PEDF），一种脂肪因子，是氧化应激、炎症、血管生成和胰岛素敏感性的调节剂。与动物和细胞培养数据相反，交感肾上腺系统的抑制并不影响人类血清 PEDF。然而，在急性β-肾上腺素能受体刺激期间，血清 PEDF 浓度降低。PEDF 可能参与脂肪组织和骨骼肌之间的串扰。
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