Kaplan R J, Rosenberg E W
Postgrad Med. 1978 Dec;64(6):52-6. doi: 10.1080/00325481.1978.11714996.
Atopic dermatitis is a chronic disease marked by exacerbations and remissions. It begins in early infancy and may persist into late adulthood. Flares of dermatitis may be precipitated by emotional stess, extremes or sudden changes in humidity or temperature, and other factors. Treatment consists primarily of the use of mild topical agents to reduce inflammation and pruritus. Long-term systemic therapy with corticosteroid is not recommended. Topical preparations containing agents that increase the local levels of cyclic adenosine monophosphate (eg, caffeine) may be useful.
特应性皮炎是一种以病情加重和缓解为特征的慢性疾病。它始于婴儿早期，可能持续到成年晚期。皮炎发作可能由情绪压力、湿度或温度的极端变化或突然变化以及其他因素引发。治疗主要包括使用温和的局部用药来减轻炎症和瘙痒。不建议长期使用皮质类固醇进行全身治疗。含有能提高局部环磷酸腺苷水平的药物（如咖啡因）的局部制剂可能有用。
