Department of Diagnostic Radiology, Saitama Medical University International Medical Center, Saitama, Japan. s
J Neuroimaging. 2013 Jan;23(1):137-40. doi: 10.1111/j.1552-6569.2011.00603.x. Epub 2011 Jun 23.
Juvenile psammomatoid ossifying fibroma (JPOF) of the sphenoid sinus is a rare subtype of ossifying fibroma of the sinonasal cavity and facial bone in young adults. Computed tomographic (CT) and magnetic resonance (MR) imaging features of JPOF have been reported, but to our knowledge, positron emission tomography (PET) findings have not been described. We present a 19-year-old woman with right visual disturbance whom we diagnosed with JPOF and describe imaging findings in her case. CT revealed a well-circumscribed fibro-osseous mass surrounding the right optic canal, with expansile, mixed soft tissue and thick bone density. MR imaging showed low signal intensity in the mass on both T(1)- and T(2)-weighted images. [(18)F]fluorodeoxyglucose ([(18)F]FDG) and [(11)C]methyl-L-methionine ([(11)C]Met) PET/CT showed abnormal uptake in the lesion, with standardized uptake values (SUV) of 6.2 ([(18)F]FDG) and 4.6 ([(11)C]Met). Familiarity with the imaging features of this rare disease aids its differentiation from other more familiar lesions to permit appropriately aggressive therapy and improve prognosis.
蝶窦少年性砂粒骨型骨纤维瘤（JPOF）是发生于青年成人鼻窦和颌面骨的一种罕见骨化性纤维瘤亚型。已有关于 JPOF 的计算机断层扫描（CT）和磁共振（MR）成像特征的报道，但据我们所知，尚未描述过正电子发射断层扫描（PET）的结果。我们报告了 1 例 19 岁女性，因右眼视觉障碍就诊，经诊断为 JPOF，并对其病例的影像学表现进行了描述。CT 显示右侧视神经管周围有一界限清楚的纤维骨性肿块，呈膨胀性，伴混合性软组织和厚骨密度。MR 成像显示肿块在 T1 和 T2 加权图像上均呈低信号强度。[(18)F]氟代脱氧葡萄糖 ([(18)F]FDG) 和 [(11)C]甲硫氨酸 ([(11)C]Met) PET/CT 显示病变摄取异常，标准摄取值（SUV）分别为 6.2([(18)F]FDG) 和 4.6([(11)C]Met)。熟悉这种罕见疾病的影像学特征有助于将其与其他更常见的病变区分开来，从而进行适当的积极治疗并改善预后。
