Chung Robert T, Montejo Julio D, Kerr Darcy A, Hong Jennifer
Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire; and.
Departments of Neurosurgery, and.
J Neurosurg Case Lessons. 2021 Sep 6;2(10):CASE21361. doi: 10.3171/CASE21361.
Juvenile psammomatoid ossifying fibroma (JPOF) is an uncommon benign fibro-osseous lesion that only rarely presents in the calvaria.
The authors reported a case of JPOF in the left parietal bone of a 20-year-old patient and reviewed the 27 other cases of JPOF occurring in the calvaria as reported in the literature.
JPOF rarely presents in the calvaria, and because diagnosis is a histopathologic one, clinicians should consider this entity when presented with a lytic, expansile mass on imaging. Little is known about the molecular mechanisms driving development of JPOF. amplification may play a role, although this was not seen in the case presented herein.
青少年砂粒样骨化性纤维瘤(JPOF)是一种罕见的良性纤维-骨病变,极少出现在颅骨。
作者报告了一例20岁患者左顶骨的JPOF病例,并回顾了文献中报道的其他27例发生在颅骨的JPOF病例。
JPOF很少出现在颅骨,由于诊断依靠组织病理学,临床医生在影像学检查发现溶骨性、膨胀性肿块时应考虑到这一病变。关于驱动JPOF发生发展的分子机制知之甚少。扩增可能起作用,尽管在本文报道的病例中未观察到。