Juvenile psammomatoid ossifying fibroma of the parietal bone and review of calvarial presentations: illustrative case.

BACKGROUND

Juvenile psammomatoid ossifying fibroma (JPOF) is an uncommon benign fibro-osseous lesion that only rarely presents in the calvaria.

OBSERVATIONS

The authors reported a case of JPOF in the left parietal bone of a 20-year-old patient and reviewed the 27 other cases of JPOF occurring in the calvaria as reported in the literature.

LESSONS

JPOF rarely presents in the calvaria, and because diagnosis is a histopathologic one, clinicians should consider this entity when presented with a lytic, expansile mass on imaging. Little is known about the molecular mechanisms driving development of JPOF. amplification may play a role, although this was not seen in the case presented herein.