Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Poland.
Clin Chim Acta. 2011 Sep 18;412(19-20):1702-11. doi: 10.1016/j.cca.2011.06.007. Epub 2011 Jun 15.
Anorexia nervosa is a complex eating disorder of unknown etiology which affects adolescent girls and young women and leads to chronic malnutrition. Clinical manifestations of prolonged semistarvation include a variety of physical features and psychiatric disorders. The study of different biological factors involved in the pathophysiology of anorexia nervosa is an area of active interest. In this review we have described the role of adipocytokines, neurotrophins, peptides of the gastrointestinal system and growth factors in appetite regulation, energy balance and insulin sensitivity in anorexia nervosa patients.
神经性厌食症是一种病因不明的复杂进食障碍，影响青少年女孩和年轻女性，并导致慢性营养不良。长期半饥饿的临床表现包括各种身体特征和精神障碍。研究涉及神经性厌食症病理生理学的不同生物学因素是一个活跃的研究领域。在这篇综述中，我们描述了脂肪细胞因子、神经营养因子、胃肠道肽和生长因子在神经性厌食症患者的食欲调节、能量平衡和胰岛素敏感性中的作用。
