REM 睡眠行为障碍筛查问卷（RBDSQ）在帕金森病患者中的应用。
Utility of the REM sleep behavior disorder screening questionnaire (RBDSQ) in Parkinson's disease patients.
机构信息
Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Japan.
出版信息
Sleep Med. 2011 Aug;12(7):711-3. doi: 10.1016/j.sleep.2011.01.015. Epub 2011 Jun 22.
OBJECTIVE
We evaluated the usefulness of the REM sleep behavior disorder (RBD) screening questionnaire (RBDSQ) among patients with Parkinson's disease (PD).
METHODS
Forty-five patients with PD were evaluated (22 male and 23 female, 72.9±9.1 years old). After patients completed the RBDSQ, we conducted interviews regarding RBD symptoms and performed polysomnographic examinations on the subjects. We then compared RBDSQ scores among the following groups: PD with RBD (n=19), PD without RBD (n=26), and idiopathic RBD (n=31, 22 male and 9 female, 67.8±6.5 years old), and estimated the cut-off score for an RBD diagnosis.
RESULTS
RBDSQ scores in PD with RBD and idiopathic RBD groups were similar and higher than those in the PD without RBD group (PD with RBD: 7.2±1.9, idiopathic RBD: 7.9±2.8, PD without RBD: 2.9±1.6). Cronbach's α for RBDSQ sub-scores was 0.73, suggesting a fair internal consistency. A receiver-operator characteristics curve revealed that a total score of 6 points on the RBDSQ represented the best cut-off value for detecting RBD (sensitivity=0.842, specificity=0.962).
CONCLUSION
RBDSQ could be a useful tool for the screening of RBD in PD patients.
目的
评估 REM 睡眠行为障碍（RBD）筛查问卷（RBDSQ）在帕金森病（PD）患者中的有用性。
方法
对 45 名 PD 患者（22 名男性，23 名女性，72.9±9.1 岁）进行评估。患者完成 RBDSQ 后，我们对其 RBD 症状进行访谈，并对受试者进行多导睡眠图检查。然后，我们比较了以下组别的 RBDSQ 评分：PD 伴 RBD（n=19）、PD 不伴 RBD（n=26）和特发性 RBD（n=31，22 名男性和 9 名女性，67.8±6.5 岁），并估计 RBD 诊断的截断分数。
结果
PD 伴 RBD 和特发性 RBD 组的 RBDSQ 评分相似且高于 PD 不伴 RBD 组（PD 伴 RBD：7.2±1.9，特发性 RBD：7.9±2.8，PD 不伴 RBD：2.9±1.6）。RBDSQ 子量表的 Cronbach's α 为 0.73，提示内部一致性尚可。受试者工作特征曲线显示，RBDSQ 总分 6 分是检测 RBD 的最佳截断值（灵敏度=0.842，特异性=0.962）。
结论
RBDSQ 可能是 PD 患者 RBD 筛查的有用工具。
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