Shin D H, Park S S, Lee J H, Park M H, Lee J D
Department of Medicine, Hanyang University School of Medicine, Seoul, Korea.
Chest. 1990 Oct;98(4):1021-3. doi: 10.1378/chest.98.4.1021.
An oncocytic variant of glomus tumor of the trachea occurred in a 47-year-old woman. She experienced intermittent cough and hemoptysis for about three years. Bronchoscopy and chest CT scan showed a small reddish polypoid tumor on the lower end of the trachea. Bronchoscopic biopsy was carefully done and was diagnosed as oncocytoma. A wedge resection of the tumor was done. Tumor cells were characterized by strongly eosinophilic granular cytoplasm on light microscopy and by numerous closely packed round or ovoid mitochondria with prominent tubular cristae on electron microscopy. They were arranged in a sheet around small vessels, as a result of which the biopsy diagnosis of oncocytoma was changed to oncocytic glomus tumor. To our knowledge, this is the first report of an oncocytic glomus tumor arising from the trachea.
一名47岁女性发生了气管嗜酸性细胞型球瘤。她经历了约三年的间歇性咳嗽和咯血。支气管镜检查和胸部CT扫描显示气管下端有一个微红的息肉样小肿瘤。仔细进行了支气管镜活检,诊断为嗜酸性细胞瘤。对肿瘤进行了楔形切除术。光镜下肿瘤细胞的特征是细胞质呈强嗜酸性颗粒状,电镜下可见大量紧密排列的圆形或椭圆形线粒体,其管状嵴突出。它们围绕小血管呈片状排列,因此活检诊断的嗜酸性细胞瘤改为嗜酸性细胞型球瘤。据我们所知,这是首例起源于气管的嗜酸性细胞型球瘤报告。