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治疗性硬质支气管镜检查用于支气管内血管球瘤:病例系列

Therapeutic rigid bronchoscopy for endobronchial glomus tumors: a case series.

作者信息

Ho Rong Lih, Jeong Byeong-Ho, Han Joungho, Kim Hojoong

机构信息

Department of Respiratory, Queen Elizabeth Hospital, Sabah, Malaysia.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

出版信息

BMC Pulm Med. 2025 Jan 24;25(1):39. doi: 10.1186/s12890-024-03466-z.

Abstract

BACKGROUND

Glomus tumors (GTs) are rare, comprising only 2% of all soft tissue tumors. Pulmonary GTs are exceptionally rare, with fewer than 80 cases reported to date. Little is known about the therapeutic outcomes of rigid bronchoscopy for endobronchial GT.

METHODS

This is a case series of four patients with endobronchial GT who underwent therapeutic rigid bronchoscopy between February 2021 and June 2024.

RESULTS

The ages of the patients in our series ranged from 32 to 75 years, and all patients were male. Cough and blood-tinged sputum were present in all patients with endobronchial GT. The tumor sizes ranged from 1 to 3 cm. Complete endoscopic resection and laser cauterization via rigid bronchoscopy were achieved in two patients. One patient had incomplete resection of a 3-cm tumor in the segmental bronchus that showed radiological evidence of bronchial wall invasion. This patient subsequently underwent lobectomy seven months after bronchoscopic resection. The fourth patient was lost to follow-up. There was no mortality throughout the follow-up periods that ranged from 2.8 to 42.5 months. Factors favoring successful rigid bronchoscopy resection for endobronchial GT include a benign tumor in the central airways without bronchial wall invasion.

CONCLUSION

Endoscopic resection and laser cauterization using rigid bronchoscopy may be a viable option for patients with endobronchial GT when surgery is not practical.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

背景

血管球瘤(GTs)较为罕见,仅占所有软组织肿瘤的2%。肺血管球瘤极为罕见,迄今为止报告的病例不足80例。关于硬质支气管镜治疗支气管内血管球瘤的治疗效果知之甚少。

方法

这是一组4例支气管内血管球瘤患者的病例系列,他们在2021年2月至2024年6月期间接受了硬质支气管镜治疗。

结果

我们系列中的患者年龄在32至75岁之间,均为男性。所有支气管内血管球瘤患者均有咳嗽和痰中带血症状。肿瘤大小在1至3厘米之间。两名患者通过硬质支气管镜实现了完全内镜切除和激光烧灼。一名患者在段支气管内有一个3厘米的肿瘤,切除不完全,影像学显示有支气管壁侵犯证据。该患者在支气管镜切除术后七个月接受了肺叶切除术。第四名患者失访。在2.8至42.5个月的随访期内无死亡病例。有利于硬质支气管镜成功切除支气管内血管球瘤的因素包括中央气道内的良性肿瘤且无支气管壁侵犯。

结论

对于手术不可行的支气管内血管球瘤患者,使用硬质支气管镜进行内镜切除和激光烧灼可能是一种可行的选择。

临床试验编号

不适用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d8a/11762895/2f7dfe642c1e/12890_2024_3466_Fig1_HTML.jpg

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本文引用的文献

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