银屑病患者多形核白细胞在体外对白三烯B4的趋化作用。
Chemotaxis of polymorphonuclear leukocytes towards LTB4 in patients with psoriasis in vitro.
作者信息
Sun R Z, Zhou D Y, Zheng M R, Yue T L
机构信息
Department of Dermatology, Changhai Hospital, Second Military Medical College.
出版信息
Chin Med J (Engl). 1990 Jul;103(7):595-8.
The random migration and chemotaxis of polymorphonuclear leukocytes (PMN) in agarose were studied in 21 patients with psoriasis and 10 healthy controls. Different concentrations of LTB4 were used as chemoattractants. The random migration and chemotaxis towards lower concentrations of LTB4 were enhanced and that towards higher concentrations of LTB4 reduced in psoriasis. The differences of body involvement, sex, and family history of psoriasis had no influence on PMN migration.
对21例银屑病患者和10名健康对照者研究了多形核白细胞（PMN）在琼脂糖中的随机迁移和趋化性。使用不同浓度的白三烯B4（LTB4）作为趋化剂。银屑病患者中，PMN对较低浓度LTB4的随机迁移和趋化性增强，而对较高浓度LTB4的趋化性降低。银屑病的皮损范围、性别及家族史差异对PMN迁移无影响。
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