Guarda L A
Department of Pathology, Florida Hospital, Orlando 32803.
Diagn Cytopathol. 1990;6(4):235-42. doi: 10.1002/dc.2840060403.
Three-hundred and seventy intraoperative cytologies are presented and compared with synchronously performed frozen sections. Cytologic smears and frozen sections were misinterpreted in 1.6% and 0.8% of cases, respectively; the rate of diagnostic errors between the two techniques is comparable given the lack of experience with intraoperative cytology at the beginning of the study. Intraoperative cytology is a suitable technique for a variety of lesions, but it is most helpful in the field of neuro-oncological pathology, certain infectious diseases, lesions of the hematopoietic system, and most epithelial tumors. Cytologic smears afford better morphologic preservation and detail than frozen sections. Techniques are outlined and discussed. Diagnostic criteria of selected cases are presented, and pitfalls are analyzed.
本文展示了370例术中细胞学检查结果，并与同期进行的冰冻切片进行了比较。细胞学涂片和冰冻切片的误诊率分别为1.6%和0.8%；鉴于研究开始时缺乏术中细胞学经验，两种技术的诊断错误率具有可比性。术中细胞学是适用于多种病变的技术，但在神经肿瘤病理学、某些传染病、造血系统病变和大多数上皮性肿瘤领域最有帮助。细胞学涂片比冰冻切片能提供更好的形态保存和细节。文中概述并讨论了相关技术。展示了部分病例的诊断标准，并分析了陷阱。
