Uchiyama Toshiya, Sakai Keiichi, Asanuma Megumi, Aoyama Tatsuro, Hongo Kazuhiro
Department of Neurosurgery, Shinshu University School of Medicine, Japan.
Neurol Med Chir (Tokyo). 2011;51(6):455-9. doi: 10.2176/nmc.51.455.
A 12-year-old girl presented with complaints of headache, lethargy, photophobia, and fever. Cerebrospinal fluid examination revealed bacterial meningitis. Magnetic resonance (MR) imaging showed a cystic lesion with peripheral enhancement in the pituitary fossa. The patient underwent transnasal-transsphenoidal surgery (TSS). The diagnosis was pituitary abscess associated with Rathke's cleft cyst. Postoperatively, the patient recovered rapidly. However, recurrence of the pituitary abscess causing meningitis occurred four times and required repeated TSS. She had diabetes insipidus and received hormone replacement. This case requiring repeated emergency surgeries shows that follow-up examinations including MR imaging and pituitary endocrine evaluation are necessary because the rate of recurrence is high in patients with pituitary abscess associated with Rathke's cleft cyst.
一名12岁女孩出现头痛、嗜睡、畏光和发热症状。脑脊液检查显示为细菌性脑膜炎。磁共振成像显示垂体窝内有一个周边强化的囊性病变。患者接受了经鼻-蝶窦手术(TSS)。诊断为与拉克氏裂囊肿相关的垂体脓肿。术后,患者恢复迅速。然而,垂体脓肿复发导致脑膜炎发生了4次,需要反复进行TSS。她患有尿崩症并接受了激素替代治疗。该病例需要反复进行急诊手术,表明包括磁共振成像和垂体内分泌评估在内的随访检查是必要的,因为与拉克氏裂囊肿相关的垂体脓肿患者复发率很高。