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超声引导下双侧腹横肌平面阻滞用于 DIEP 皮瓣乳房再造术后镇痛。

Ultrasound-guided bilateral transversus abdominis plane block for postoperative analgesia after breast reconstruction by DIEP flap.

机构信息

Créteil, France From the Departments of Plastic and Surgery and Anesthesiology and Reanimation, GHU A. Chenevier H. Mondor, Université Paris Est Créteil.

出版信息

Plast Reconstr Surg. 2011 Jul;128(1):44-55. doi: 10.1097/PRS.0b013e3182174090.

Abstract

BACKGROUND

Autologous breast reconstruction by deep inferior epigastric perforator (DIEP) flap provides higher postoperative pain at the abdominal donor site than at the thoracic one. The authors evaluated the analgesic efficacy of ultrasound-guided transverse abdominis plane block for postoperative analgesia after immediate breast reconstruction by DIEP flap.

METHODS

The authors conducted an open prospective study of 30 consecutive women undergoing immediate DIEP flap breast reconstruction after modified radical mastectomy for cancer. The last 15 patients received a bilateral ultrasound-guided block with 1.5 mg/kg ropivacaine on each side after DIEP flap harvesting, under general anesthesia. All patients received postoperative acetaminophen and patient-controlled intravenous morphine and were assessed for morphine use, satisfaction with pain relief, and adverse effects.

RESULTS

Morphine requirements were significantly lower in the block group than in the control group for the 0- to 12-hour (17.7 mg versus 22.7 mg, p = 0.0047) and 12- to 24-hour (14.2 mg versus 17.4 mg, p = 0.01) intervals but not for the 24- to 36-hour (11.3 mg versus 12.2 mg, p = 0.30) and 36- to 48-hour (8.6 mg versus 8.4 mg, p = 0.65) intervals. Cumulative morphine use was lower in the block group than in the control group for the first 24 hours (32.0 mg versus 40.2 mg, p = 0.0057) and the first 48 hours (51.7 mg versus 60.5 mg, p = 0.03). There was no complication attributable to the block, with an average follow-up of 9 months.

CONCLUSIONS

Bilateral ultrasound-guided transversus abdominis plane block after breast reconstruction by DIEP flap reduces the interval and cumulative morphine requirements for the first 24 and 48 hours, respectively.

CLINICAL QUESTION/LEVEL OF EVIDENCE: : Therapeutic, II.(Figure is included in full-text article.).

摘要

背景

与胸壁供区相比,采用腹壁下动脉穿支皮瓣(DIEP)进行自体乳房重建术后,腹部供区的术后疼痛更明显。作者评估了超声引导下腹横肌平面阻滞(TAPB)在 DIEP 皮瓣即刻乳房重建术后的镇痛效果。

方法

作者对 30 例因癌症接受改良根治性乳房切除术的患者进行了一项开放性前瞻性研究,这些患者均在接受 DIEP 皮瓣游离后,于全身麻醉下接受双侧超声引导 TAPB,每侧注射 1.5mg/kg 罗哌卡因。所有患者均接受术后对乙酰氨基酚和患者自控静脉注射吗啡,并评估吗啡用量、疼痛缓解满意度和不良反应。

结果

与对照组相比,阻滞组在 0-12 小时(17.7mg 比 22.7mg,p=0.0047)和 12-24 小时(14.2mg 比 17.4mg,p=0.01)的吗啡需求量显著降低,但在 24-36 小时(11.3mg 比 12.2mg,p=0.30)和 36-48 小时(8.6mg 比 8.4mg,p=0.65)的吗啡需求量没有显著降低。在 24 小时(32.0mg 比 40.2mg,p=0.0057)和 48 小时(51.7mg 比 60.5mg,p=0.03)内,阻滞组的累积吗啡用量均低于对照组。

结论

DIEP 皮瓣乳房重建术后行双侧超声引导 TAPB 可分别减少术后 24 小时和 48 小时内吗啡的间隔和累积需求。

临床问题/证据水平:治疗性,II 级。(全文包含图表。)

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