Baklavadzhian O I, Eganova V S, Kasparova S R, Khudoian E A
Fiziol Zh SSSR Im I M Sechenova. 1990 Apr;76(4):438-45.
Effects of i.v. administration of cholino- and adrenergic blocking agents on limbic-sympathetic discharges of L2-L3 white rami, evoked by stimulation of the anterior, visceral area of the limbic cortex and on arterial blood pressure were studied in anesthetized cats. M- and N-cholinoreceptor blocking agents atropine and ganglerone do not induce any apparent changes in limbic-sympathetic discharge and the blood pressure level. Beta-adrenoreceptor blocking agent propranolol evoked a small fall of the blood pressure with no apparent changes of limbic-sympathetic discharges. Alpha-adrenoreceptor blocking agent phenotolamine evoked obvious drop of the blood pressure and, in two out of eight experiments, a marked increase of the amplitude of limbic-sympathetic evoked discharges. Neurochemical regulatory mechanism of limbic-spinal sympathetic activity are discussed.
在麻醉猫身上，研究了静脉注射胆碱能和肾上腺素能阻断剂对由刺激边缘皮质的前内脏区所诱发的L2 - L3白交通支的边缘 - 交感神经放电以及动脉血压的影响。M和N胆碱能受体阻断剂阿托品和甘罗溴铵未引起边缘 - 交感神经放电和血压水平的任何明显变化。β肾上腺素能受体阻断剂普萘洛尔使血压略有下降，而边缘 - 交感神经放电无明显变化。α肾上腺素能受体阻断剂酚妥拉明使血压明显下降，并且在8个实验中的2个实验中，边缘 - 交感神经诱发放电的幅度显著增加。文中讨论了边缘 - 脊髓交感神经活动的神经化学调节机制。
