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[三叉神经阻断后去大脑迷走神经切断猫对二氧化碳的通气敏感性]

[The ventilatory sensitivity of decerebrate vagotomized cats to CO2 after blockade of the trigeminal nerves].

作者信息

Sukhova G K, Nazaruk A V

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1990 May;76(5):580-7.

PMID:2170190
Abstract

The dependence of the lung ventilation per minute (VI) on the CO2 partial pressure in the terminal portion of expired air (PET, CO2) was studied prior to and after the blockade of trigeminal nerves in decerebrated vagotomized cats. The thermal blockade entailed a 5.5 mm Hg shift of the regression curve to the left. The point of crossing of the curve with the pCO2 axis shifted from 22.6 to 17.1 mm Hg. The curve inclination changed insignificantly. Prior to and after the blockade, a positive correlation existed between VI and respiratory volumes, the connection between VI and the respiration rate being absent. Tonic afferents of trigeminal nerves seem to reduce the responsiveness of respiratory mechanism to chemoreceptor afferent input, decreasing ventilatory responses to CO2.

摘要

在切断迷走神经的去大脑猫中,在三叉神经阻断前后,研究了每分钟肺通气量(VI)对呼出气体终末部分二氧化碳分压(PET,CO2)的依赖性。热阻断使回归曲线向左移动5.5毫米汞柱。曲线与pCO2轴的交点从22.6毫米汞柱移至17.1毫米汞柱。曲线倾斜度变化不明显。在阻断前后,VI与呼吸量之间存在正相关,而VI与呼吸频率之间不存在联系。三叉神经的紧张性传入似乎降低了呼吸机制对化学感受器传入输入的反应性,降低了对CO2的通气反应。

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