Yong-Yuan Z, Rizzetto M, Bonino F, Verme G, Lien-Jie H
Department of Infectious Disease, Tongji Hospital, Tongji Medical University, Wuhan, P. R. China.
Hepatogastroenterology. 1990 Aug;37(4):411-2.
The prevalence of HDAg in the liver of Chinese patients with chronic hepatitis and hepatocellular carcinoma was determined using direct immunofluorescence and immunoperoxidase. Overall, 6 patients (6.31%) out of 95 HBsAg carriers with inflammatory liver disease and neoplasia were found to be HDAg positive. HDAg was detected in the livers of 6 (7.59%) out of 79 chronic hepatitis patients. The relative frequency of HDAg in cirrhosis-B, CAH-B and CPH-B was 14.3%, 7.1%, and 5.89%, respectively. These results suggest that a sizeable number of HBsAg carriers are also carriers of HDV. In view of the large number of HBV carriers in China, the relatively minor but distinct presence of HDV represents an important health problem.
采用直接免疫荧光法和免疫过氧化物酶法测定了中国慢性肝炎和肝细胞癌患者肝脏中丁型肝炎病毒抗原（HDAg）的流行情况。总体而言，95例患有炎症性肝病和肿瘤的乙肝表面抗原（HBsAg）携带者中，有6例（6.31%）被发现HDAg呈阳性。79例慢性肝炎患者中，有6例（7.59%）的肝脏检测到HDAg。在肝硬化-B型、慢性活动性肝炎-B型和慢性迁延性肝炎-B型中，HDAg的相对检出率分别为14.3%、7.1%和5.89%。这些结果表明，相当数量的HBsAg携带者也是丁型肝炎病毒（HDV）携带者。鉴于中国乙肝携带者数量众多，HDV相对较少但明显的存在是一个重要的健康问题。
