Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, 2725, Chemin Sainte-Foy, QC, G1V 4G5, Canada.
Expert Rev Respir Med. 2011 Jun;5(3):377-93. doi: 10.1586/ers.11.34.
Asthma is often associated with various comorbidities. The most frequently reported asthma comorbid conditions include rhinitis, sinusitis, gastroesophageal reflux disease, obstructive sleep apnea, hormonal disorders and psychopathologies. These conditions may, first: share a common pathophysiological mechanism with asthma; second: influence asthma control, its phenotype and response to treatment; and third: be more prevalent in asthmatic patients but without obvious influence on this disease. For many of these, how they interact with asthma remains to be further documented, particularly for severe asthma. If considered relevant, they should, however, be treated appropriately. Further research is needed on the relationships between these conditions and asthma.
哮喘常伴有多种合并症。最常报告的哮喘合并症包括鼻炎、鼻窦炎、胃食管反流病、阻塞性睡眠呼吸暂停、激素紊乱和精神病理学。这些情况可能首先：与哮喘有共同的病理生理机制；其次：影响哮喘的控制、表型和对治疗的反应；第三：在哮喘患者中更为普遍，但对该疾病没有明显影响。对于其中许多疾病，它们与哮喘的相互作用仍有待进一步记录，特别是对于严重哮喘。如果认为相关，应适当治疗。需要进一步研究这些疾病与哮喘之间的关系。
