Derebery Jennifer, Meltzer Eli, Nathan Robert A, Stang Paul E, Campbell Ulka B, Corrao Marlo, Stanford Richard
House Clinic, Los Angeles, CA, USA.
Otolaryngol Head Neck Surg. 2008 Aug;139(2):198-205. doi: 10.1016/j.otohns.2008.05.019.
To assess the burden of nasal symptoms in the United States (U.S.) and the comorbid conditions associated with nasal symptoms.
A self-administered screening questionnaire and follow-up survey was sent to targeted households from a representative sample of 15,000 households in the U.S. Subjects with comorbid asthma completed the Asthma Control Test (ACT).
Out of 7024 evaluable subjects who responded, 3831 subjects were classified as rhinitis "sufferers." Individuals with active rhinitis symptoms were 1.5 to 4.5 times more likely to suffer from comorbid conditions including asthma, conjunctivitis, otitis media, sinusitis, eczema, food and insect bite allergies, migraine, and depression. Almost half of all respondents with moderate or severe rhinitis symptoms and comorbid asthma had poorly controlled asthma as defined by an ACT score of < or =19.
A strong relationship exists between rhinitis symptoms and various comorbidities, including asthma, in the U.S. population. Poorly controlled rhinitis contributes to the public health burden of rhinitis and asthma.
评估美国鼻症状的负担以及与鼻症状相关的共病情况。
向美国15000户代表性家庭样本中的目标家庭发送了一份自行填写的筛查问卷和随访调查。患有共病哮喘的受试者完成哮喘控制测试（ACT）。
在7024名有回应的可评估受试者中，3831名受试者被归类为鼻炎“患者”。有活动性鼻炎症状的个体患包括哮喘、结膜炎、中耳炎、鼻窦炎、湿疹、食物和昆虫叮咬过敏、偏头痛和抑郁症在内的共病的可能性高出1.5至4.5倍。在所有有中度或重度鼻炎症状且患有共病哮喘的受访者中，几乎一半人的哮喘控制不佳，根据ACT评分<或=19来定义。
在美国人群中，鼻炎症状与包括哮喘在内的各种共病之间存在密切关系。控制不佳的鼻炎加重了鼻炎和哮喘的公共卫生负担。
