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根治性前列腺切除术后尿失禁伴膀胱功能障碍患者植入人工尿道括约肌后尿动力学参数的演变

Urodynamic parameters evolution after artificial urinary sphincter implantation for post-radical prostatectomy incontinence with concomitant bladder dysfunction.

作者信息

Afraa Tala Al, Campeau Lysanne, Mahfouz Wally, Corcos Jacques

机构信息

Department of Urology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

出版信息

Can J Urol. 2011 Jun;18(3):5695-8.

PMID:21703042
Abstract

INTRODUCTION

Urodynamic assessment is strongly recommended before artificial urinary sphincter (AUS) implantation. Detrusor overactivity (DO) and/or hypersensitivity and/or mild loss of compliance are frequently demonstrated in post prostatectomy incontinence. The aim of this study was to evaluate urodynamic parameter changes before and after AUS implantation in patients with urinary incontinence post-radical prostatectomy (RP) and concomitant urodynamic bladder abnormalities.

MATERIALS AND METHODS

We performed a retrospective review of charts pre- and post-AUS implantation. Sixteen out of a cohort of 52 patients met our inclusion criteria: stress urinary incontinence (SUI) due to RP and bladder dysfunction (early bladder sensation and/or low compliance and/or small bladder capacity and/or the presence of DO).

RESULTS

The mean age of these 16 patients was 68 ± 6.3 years, and the duration of incontinence was 3 ± 2.7 years. The number of pads/day was 5.7 ± 2.3 before AUS implantation, and 1 ± 0.7 after implantation. Average time for the last post-implantation UDS was 43 months (range 7 to 73 months). Comparison of pre- and post-AUS implantation urodynamic parameters revealed statistically significant improvement in bladder capacity from 271 ± 117 to 295.6 ± 151 mL (p = 0.05), bladder compliance from 7.6 ± 3.95 to 12.5 ± 10.3 mL/cmH2O (p = 0.03), and decrease in DO from 50% to 25% on cystometrograms.

CONCLUSION

Preoperative urodynamic abnormalities improved after AUS implantation. Thus, mild bladder dysfunction should not be a contraindication to AUS placement for SUI post-RP.

摘要

引言

强烈建议在植入人工尿道括约肌(AUS)之前进行尿动力学评估。前列腺切除术后尿失禁患者常表现出逼尿肌过度活动(DO)和/或超敏反应和/或顺应性轻度丧失。本研究的目的是评估根治性前列腺切除术(RP)后尿失禁并伴有尿动力学膀胱异常的患者在植入AUS前后的尿动力学参数变化。

材料与方法

我们对AUS植入前后的病历进行了回顾性研究。52例患者中有16例符合我们的纳入标准:因RP导致的压力性尿失禁(SUI)和膀胱功能障碍(早期膀胱感觉和/或低顺应性和/或膀胱容量小和/或存在DO)。

结果

这16例患者的平均年龄为68±6.3岁,尿失禁持续时间为3±2.7年。植入AUS前每天使用的尿垫数为5.7±2.3片,植入后为1±0.7片。最后一次植入后尿动力学检查的平均时间为43个月(范围7至73个月)。AUS植入前后尿动力学参数的比较显示,膀胱容量从271±117 mL显著改善至295.6±151 mL(p = 0.05),膀胱顺应性从7.6±3.95 mL/cmH2O改善至12.5±10.3 mL/cmH2O(p = 0.03),膀胱压力容积测定时DO从50%降至25%。

结论

植入AUS后术前尿动力学异常得到改善。因此,轻度膀胱功能障碍不应成为RP后SUI患者植入AUS的禁忌证。

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