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[注意缺陷障碍:为期1年的多学科观察性研究]

[Attention deficit disorder: multidisciplinary observational study over 1 year].

作者信息

Chambry J, Billard C, Guinard M, Lacaze E, Idiart M-E, Delteil-Pinton F, Cohen de Lara A

机构信息

Inserm U669, fondation Vallée, CHU de Bicêtre, université Paris VII et Paris XI, 94275 Le-Kremlin-Bicêtre, France.

出版信息

Encephale. 2011 Jun;37(3):180-90. doi: 10.1016/j.encep.2011.01.012. Epub 2011 Mar 5.

DOI:10.1016/j.encep.2011.01.012
PMID:21703433
Abstract

INTRODUCTION

In France, attention deficit disorder (ADHD) has traditionally met with two opposing approaches (biological and psychoanalytic). This conflict led us to conduct a multidisciplinary observational study, on a group of 36 children over a period of 1 year.

METHODS

Thirty-six children with ADHD diagnostic (DSM IV), not treated by MPH were included. Initial "multi-field" evaluation (T0) consisted of: neuro-paediatric consultation (Conners questionnaire, Child Behaviour Checklist, reading and writing scores by French tests); semi-structured child psychiatric interview (DSM-IV axis I), structural hypothesis (CFTMEA), existence of narcissistic fragility, parents/child interactions; neuropsychological standardized evaluation (attention and executive functions); psychodynamic interview and projective tests (Rorscharch, CAT or TAT). A therapeutic project is proposed combining MPH and psychotherapy according to the results. A new evaluation 1 year later (T1) included a consultation and a neuropsychological evaluation. RESULTS T0: All parental questionnaires appreciating attention deficit and hyperactivity/impulsivity were significantly pathological. The neuropsychological evaluation showed usual characteristics of ADHD with individual differences. The psychiatric evaluation revealed the frequency of comorbidity in axis I (23% of children with more than two diagnoses, 57% with anxiety disorder, 23 and 3% with oppositional and conduct disorder). FOLLOW UP (T1): Thirty-one children were re-examined (20 treated by MPH and 11 not treated because of parental refusal or particular psychopathological situations). Psychoanalytical psychotherapy, proposed to 28 children, was undertaken with only 19. An improvement in scores for attention and executive tests was registered only in the treated group.

DISCUSSION

The tests confirm deficits of attention and executive functions without correlation with the scores of questionnaires, underlining the need for a neuropsychological evaluation to objectify attention disorders. Projective tests refine and enrich psychiatric evaluation and showed that half of the children had borderline organization. However, structural hypotheses were heterogeneous, suggesting the need for specific therapeutic projects to be devised according to each child. The treated children were the only ones to improve attention deficit. On the other hand, the scores of anxiety are not improved by MPH, emphasizing the indications of psychotherapy if comorbidity is present. Psychotherapeutic care was carried out only among part of the population, because of parental reservations, exacerbated by differences of opinion among professionals and lack of access.

CONCLUSION

This study is innovative, providing precise data on ADHD from a multidisciplinary perspective. Psychopathological comorbidity is high in this population, so the concept of ADHD cannot be limited to a cognitive point of view. These elements and doubts regarding the efficacy of behavioural therapies suggest the need for a rigorous evaluation of analytical psychotherapies independent of MPH to treat attention deficit.

摘要

引言

在法国,注意力缺陷多动障碍(ADHD)传统上有两种对立的治疗方法(生物学方法和精神分析方法)。这种冲突促使我们对一组36名儿童进行了为期1年的多学科观察研究。

方法

纳入36名诊断为ADHD(DSM-IV)且未接受哌甲酯治疗的儿童。初始的“多领域”评估(T0)包括:神经儿科会诊(康纳斯问卷、儿童行为检查表、法语测试的读写分数);半结构化儿童精神病学访谈(DSM-IV轴I)、结构假设(CFTMEA)、自恋脆弱性的存在、父母/孩子互动;神经心理学标准化评估(注意力和执行功能);心理动力学访谈和投射测试(罗夏墨迹测验、儿童统觉测验或主题统觉测验)。根据结果提出了一项结合哌甲酯和心理治疗的治疗方案。1年后的新评估(T1)包括一次会诊和一次神经心理学评估。结果T0:所有评估注意力缺陷和多动/冲动的家长问卷均显著异常。神经心理学评估显示了ADHD的常见特征及个体差异。精神病学评估揭示了轴I共病的频率(23%的儿童有两种以上诊断,57%有焦虑症,23%和3%有对立违抗障碍和品行障碍)。随访(T1):31名儿童接受了复查(20名接受了哌甲酯治疗,11名因家长拒绝或特殊心理病理情况未接受治疗)。向28名儿童提议进行精神分析心理治疗,只有19名儿童接受了治疗。仅在治疗组中注意力和执行测试分数有所提高。

讨论

测试证实了注意力和执行功能的缺陷,且与问卷分数无关,强调了进行神经心理学评估以客观化注意力障碍的必要性。投射测试完善并丰富了精神病学评估,显示一半的儿童存在边缘性组织问题。然而,结构假设是异质性的,表明需要根据每个儿童制定具体的治疗方案。接受治疗的儿童是唯一注意力缺陷得到改善的。另一方面,哌甲酯并未改善焦虑分数,强调了如果存在共病则需要进行心理治疗。由于家长的保留态度,以及专业人员之间的意见分歧和缺乏治疗途径,心理治疗仅在部分人群中开展。

结论

本研究具有创新性,从多学科角度提供了关于ADHD的精确数据。该人群中心理病理共病率很高,因此ADHD的概念不能局限于认知角度。这些因素以及对行为疗法疗效的质疑表明,需要对独立于哌甲酯的分析性心理疗法治疗注意力缺陷进行严格评估。

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