Department of Physical Medicine and Rehabilitation, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
PM R. 2011 Jun;3(6 Suppl 1):S59-63. doi: 10.1016/j.pmrj.2011.05.001.
Exercise-based therapies are the cornerstone of rehabilitation programs. While the benefits of exercise on systemic and tissue function are generally accepted, mechanisms underlying these benefits are sometimes poorly understood. An improved understanding of the effects of mechanical loading on molecular and cellular processes has the potential to lead to more disease-specific and efficacious exercise-based therapies. The purpose of this paper is to review the current literature examining the role of mechanical signaling on muscle and cartilage biology.
基于运动的疗法是康复计划的基石。虽然运动对全身和组织功能的益处已被普遍接受，但这些益处的机制有时却理解得不够透彻。对机械负荷对分子和细胞过程的影响有更深入的了解，有可能导致更具针对性和更有效的基于运动的治疗方法。本文的目的是回顾目前关于机械信号在肌肉和软骨生物学中作用的文献。
