在一项使用两种招募方法的结直肠癌病例对照研究中，选择人群对照的参与率。
Participation rates in the selection of population controls in a case-control study of colorectal cancer using two recruitment methods.
作者信息
Castaño-Vinyals Gemma, Nieuwenhuijsen Mark J, Moreno Víctor, Carrasco Estela, Guinó Elisabet, Kogevinas Manolis, Villanueva Cristina M
机构信息
Center for Research in Environmental Epidemiology, Barcelona, Spain.
出版信息
Gac Sanit. 2011 Sep-Oct;25(5):353-6. doi: 10.1016/j.gaceta.2010.05.011. Epub 2011 Jun 23.
OBJECTIVES
Low participation rates in the selection of population controls are an increasing concern for the validity of case-control studies worldwide.
METHODS
We conducted a pilot study to assess two approaches to recruiting population controls in a study of colorectal cancer, including a face-to-face interview and blood sample collection. In the first approach, persons identified through a population roster were invited to participate through a telephone call by an interviewer telephoning on behalf of our research center. In the second approach, individuals were identified from the lists of selected family practitioners and were telephoned on behalf of the family practitioner.
RESULTS
When the second method was used, participation rates increased from 42% to 57% and the percentage of refusals decreased from 47% to 13%. The reasons for refusing to participate did not differ significantly between the two methods.
CONCLUSIONS
Contact through the family practitioner yielded higher response rates in population controls in the study area.
目的
在全球范围内，人群对照选择中的低参与率日益成为病例对照研究有效性的一个令人担忧的问题。
方法
我们进行了一项试点研究，以评估在一项结直肠癌研究中招募人群对照的两种方法，包括面对面访谈和血样采集。在第一种方法中，通过人口名册确定的人员由代表我们研究中心的访谈员通过电话邀请参与。在第二种方法中，从选定的家庭医生名单中识别出个体，并由家庭医生代表致电。
结果
使用第二种方法时，参与率从42%提高到57%，拒绝率从47%降至13%。两种方法之间拒绝参与的原因没有显著差异。
结论
通过家庭医生进行联系在研究区域的人群对照中产生了更高的回应率。
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