Department of Organismic Biology, Neurosignaling Unit, University of Salzburg, Hellbrunnerstr 34, A-5020 Salzburg, Austria.
Neurosci Biobehav Rev. 2011 Oct;35(9):1989-99. doi: 10.1016/j.neubiorev.2011.06.005. Epub 2011 Jun 16.
This paper reviews the use of music as an adjuvant to the control of pain, especially in medical procedures. Surgery causes stress and anxiety that exacerbates the experience of pain. Self-report of and physiological measures on post-surgical patients indicate that music therapy or music stimulation reduces the perception of pain, both alone and when part of a multimodal pain management program, and can reduce the need for pharmaceutical interventions. However, multimodal pain therapy, including non-pharmacological interventions after surgery, is still rare in medical practice. We summarize how music can enhance medical therapies and can be used as an adjuvant with other pain-management programs to increase the effectiveness of those therapies. As summarized, we currently know that musical pieces chosen by the patient are commonly, but not always, more effective than pieces chosen by another person. Further research should focus both on finding the specific indications and contra-indications of music therapy and on the biological and neurological pathways responsible for those findings (related evidence has implicated brain opioid and oxytocin mechanisms in affective changes evoked by music). In turn, these findings will allow medical investigators and practitioners to design guidelines and reliable, standardized applications for this promising method of pain management in modern medicine.
本文综述了音乐作为控制疼痛的辅助手段的应用,特别是在医疗程序中。手术会引起压力和焦虑,从而加剧疼痛的体验。术后患者的自我报告和生理测量表明,音乐疗法或音乐刺激可单独或作为多模式疼痛管理方案的一部分,减轻疼痛感知,还可以减少对药物干预的需求。然而,多模式疼痛治疗,包括手术后的非药物干预,在医学实践中仍然很少见。我们总结了音乐如何增强医疗疗法,并可以用作其他疼痛管理方案的辅助手段,以提高这些疗法的效果。综上所述,我们目前知道,患者选择的乐曲通常比其他人选择的乐曲更有效,但并非总是如此。进一步的研究应既关注音乐疗法的具体适应证和禁忌证,也关注负责这些发现的生物学和神经通路(相关证据表明,音乐引起的情感变化与大脑阿片和催产素机制有关)。反过来,这些发现将使医学研究人员和从业者能够为这种有前途的现代医学疼痛管理方法设计指南和可靠的标准化应用。