Department of Physiology and Biophysics, Georgetown University Medical Center, room 225 3900 Reservoir Rd, N.W., Washington DC 20057, United States.
Pharmacol Res. 2011 Oct;64(4):316-8. doi: 10.1016/j.phrs.2011.05.020. Epub 2011 Jun 16.
This historical review of the electrophysiology laboratory complemented the activity of the various research teams at the Fidia Georgetown Institute for the Neurosciences and it was the fulfillment of Dr. Erminio Costa's dream to be able to study the inhibitory and excitatory synapse in the central nervous system. These studies were facilitated by the development of the patch clamp technique that allows the functional testing of several of the biochemical and pharmacological hypotheses. The studies described here were the results of the hard work of all the collaborators involved in the projects that will never forget the passionate and stimulating discussion with Dr Costa during and after the development of these projects.
本文对电生理实验室进行了历史回顾，这与 Fidia 乔治敦神经科学研究所的各个研究团队的活动相得益彰，也是 Erminio Costa 博士的梦想得以实现，即能够研究中枢神经系统中的抑制性和兴奋性突触。这些研究得益于 patch clamp 技术的发展，该技术允许对多个生化和药理学假设进行功能测试。这里描述的研究是所有参与项目的合作者辛勤工作的结果，他们永远不会忘记在这些项目的开发过程中和之后与 Costa 博士进行的热烈而富有启发性的讨论。
