Verkhratsky Alexei, Krishtal O A, Petersen Ole H
Faculty of Life Sciences, The University of Manchester, Manchester, M13 9PT, UK.
Pflugers Arch. 2006 Dec;453(3):233-47. doi: 10.1007/s00424-006-0169-z. Epub 2006 Oct 28.
The development of electrophysiology is traced from the early beginnings represented by the work of the Dutch microscopist, Jan Swammerdam, in the 17th century through the first notion of an aqueous transmembrane pore as a substrate of excitability made by Luigi Galvani in late 18th century to the invention late in the 20th century of the patch-clamp technique by Erwin Neher and Bert Sakmann.
电生理学的发展历程可追溯到17世纪荷兰显微镜学家扬·斯瓦默丹的研究工作,直至18世纪末路易吉·伽伐尼提出的关于作为兴奋性基础的跨膜水相孔道的首个概念,再到20世纪末埃尔温·内尔和伯特·萨克曼发明的膜片钳技术。