Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada.
Fertil Steril. 2011 Aug;96(2):336-9. doi: 10.1016/j.fertnstert.2011.05.076. Epub 2011 Jun 25.
To evaluate the effect of body mass index (BMI) on in vitro maturation (IVM) outcomes in women with polycystic ovaries.
Retrospective, cohort study.
Tertiary IVF unit.
PATIENT(S): One hundred thirteen women with polycystic ovaries.
INTERVENTION(S): One hundred sixteen cycles of IVM. Patients were divided into subgroups according to their BMI: underweight, normal weight, overweight, obese, and morbidly obese. We evaluated the effects of BMI on the number of oocytes matured in vivo, maturation rate in vitro, fertilization and cleavage rates, number of embryos transferred, implantation rates, pregnancy rates, and delivery rates.
MAIN OUTCOME MEASURE(S): Pregnancy rate and delivery rate.
RESULT(S): The number and quality of oocytes among women with different BMIs were similar. There was no significant difference in the endometrial thickness and rates of implantation, pregnancy, and delivery among women with different BMIs. The pregnancy rate in underweight women was 50%, normal weight 47.9%, overweight 29.1%, obese 27.2%, and in morbidly obese women was 30.7%. The miscarriage and delivery rates were also similar.
CONCLUSION(S): The results of IVM are independent of BMI.
评估体重指数（BMI）对多囊卵巢妇女体外成熟（IVM）结局的影响。
回顾性队列研究。
三级试管婴儿单位。
113 名多囊卵巢患者。
进行了 116 个 IVM 周期。根据 BMI 将患者分为亚组：体重不足、正常体重、超重、肥胖和病态肥胖。我们评估了 BMI 对体内成熟卵母细胞数量、体外成熟率、受精和卵裂率、移植胚胎数量、着床率、妊娠率和分娩率的影响。
妊娠率和分娩率。
不同 BMI 妇女的卵母细胞数量和质量相似。不同 BMI 妇女的子宫内膜厚度和着床率、妊娠率和分娩率无显著差异。体重不足的妇女妊娠率为 50%，正常体重为 47.9%，超重为 29.1%，肥胖为 27.2%，病态肥胖为 30.7%。流产率和分娩率也相似。
IVM 的结果与 BMI 无关。
