Effects of different body mass indices on in vitro maturation in women with polycystic ovaries.

OBJECTIVE

To evaluate the effect of body mass index (BMI) on in vitro maturation (IVM) outcomes in women with polycystic ovaries.

DESIGN

Retrospective, cohort study.

SETTING

Tertiary IVF unit.

PATIENT(S): One hundred thirteen women with polycystic ovaries.

INTERVENTION(S): One hundred sixteen cycles of IVM. Patients were divided into subgroups according to their BMI: underweight, normal weight, overweight, obese, and morbidly obese. We evaluated the effects of BMI on the number of oocytes matured in vivo, maturation rate in vitro, fertilization and cleavage rates, number of embryos transferred, implantation rates, pregnancy rates, and delivery rates.

MAIN OUTCOME MEASURE(S): Pregnancy rate and delivery rate.

RESULT(S): The number and quality of oocytes among women with different BMIs were similar. There was no significant difference in the endometrial thickness and rates of implantation, pregnancy, and delivery among women with different BMIs. The pregnancy rate in underweight women was 50%, normal weight 47.9%, overweight 29.1%, obese 27.2%, and in morbidly obese women was 30.7%. The miscarriage and delivery rates were also similar.

CONCLUSION(S): The results of IVM are independent of BMI.