Department of Nuclear Medicine, John Hunter Hospital, New Lambton, New South Wales, Australia.
Nat Med. 2011 Jun 26;17(7):809-11. doi: 10.1038/nm.2382.
Snake venom toxins first transit the lymphatic system before entering the bloodstream. Ointment containing a nitric oxide donor, which impedes the intrinsic lymphatic pump, prolonged lymph transit time in rats and humans and also increased rat survival time after injection of venom. This pharmacological approach should give snakebite victims more time to obtain medical care and antivenom treatment.
蛇毒毒素首先通过淋巴系统进入血液循环。含有一氧化氮供体的软膏会阻碍内在的淋巴泵，从而延长大鼠和人类的淋巴转运时间，并延长注射毒液后大鼠的存活时间。这种药理学方法应该能让被蛇咬伤的受害者有更多的时间获得医疗护理和抗蛇毒血清治疗。
