Coman C, Popescu L V, Micu V, Iurea A
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1978 Oct-Dec;27(4):227-39.
The authors make an analysis of the experience acquired in the Clinic of Thoracic Surgery of Bucharest, based on interventions carried out in 42 cases of bronchial adenoma hospitalized between 1962 and 1976. The fact is stressed that in none of the 42 operated patients was the carcinoid syndrome encountered with any of its specific manifestations. Also on the basis of the experience obtained the bronchologic criteria for benignity of this type of tumour (absence of the infiltration in the mucosa, surrounding the tumour) is considered as non-significant because there are frequently areas of malignant transformation inside the tumour itself, or at its lower pole that cannot be explored by bronchoscopy. Surgical treatment of bronchial adenoma included a wide range of techniques, from simple lobectomies to bronchoanastomotic interventions, and resections of the trachea. The study of postoperative results showed a good prognosis and survivals of appreciable duration only when the intervention was carried out in the I-st and the II-nd stages of the disease. This also stresses the necessity for an early diagnosis and rapid surgery in these bronchial adenomatous tumours (most of which are of the carcinoid type).
作者基于1962年至1976年间在布加勒斯特胸外科诊所对42例支气管腺瘤患者实施的干预措施,对所积累的经验进行了分析。着重指出的是,在这42例接受手术的患者中,均未出现类癌综合征的任何特异性表现。同样基于所获得的经验,该类型肿瘤的良性支气管学标准(肿瘤周围黏膜无浸润)被认为意义不大,因为肿瘤内部或其下极常常存在恶性转化区域,而支气管镜检查无法探查这些区域。支气管腺瘤的外科治疗包括多种技术,从简单的肺叶切除到支气管吻合手术以及气管切除。对术后结果的研究表明,只有在疾病的第一期和第二期进行干预时,才会有良好的预后和较长的生存期。这也强调了对这些支气管腺瘤性肿瘤(其中大多数为类癌类型)进行早期诊断和快速手术的必要性。