基于聚乙烯亚胺的高效固载点击催化剂体系的简便制备方法。

Facile Access to an Efficient Solid-Supported Click Catalyst System Based on Poly(ethyleneimine).

作者信息

Bonami Lies, Van Camp Wim, Van Rijckegem Dieter, Du Prez Filip E

机构信息

Department of Organic Chemistry, Polymer Chemistry Research Group, Ghent University, Krijgslaan 281 S4 bis, B-9000 Ghent, Belgium.

出版信息

Macromol Rapid Commun. 2009 Jan 2;30(1):34-8. doi: 10.1002/marc.200800607. Epub 2008 Dec 12.

DOI:10.1002/marc.200800607

PMID:21706535

Abstract

A novel heterogeneous copper(I) catalyst system, which is based on readily available poly(ethyleneimine), has been used as a recyclable catalyst for Cu(I) catalyzed "click" 1,3 dipolar cycloaddition reactions of azides and alkynes in organic media. Branched poly(ethyleneimine) was first methylated and then cross-linked with 1,9-dibromononane. Subsequently, after the immobilization of Cu(I)Br, this system was applied for heterogeneous copper catalyzed click chemistry of a few model reagents and polymeric compounds.

摘要

一种基于易于获得的聚乙烯亚胺的新型多相铜（I）催化剂体系，已被用作可循环使用的催化剂，用于在有机介质中铜（I）催化的叠氮化物和炔烃的“点击”1,3-偶极环加成反应。支化聚乙烯亚胺首先进行甲基化，然后与1,9-二溴壬烷交联。随后，在固定化Cu（I）Br之后，该体系被应用于几种模型试剂和聚合物化合物的多相铜催化点击化学。