Division of Urology, Penn State Milton S Hershey Medical Center, Hershey, PA 17033-0850, USA.
Expert Rev Anticancer Ther. 2011 Jun;11(6):879-91. doi: 10.1586/era.11.70.
The past few decades have witnessed a steady increase in the number of newly diagnosed small renal masses. Although historically managed by surgical resection, many of these small renal masses are now noted to be amenable to less invasive treatment modalities including thermal ablation or active surveillance. Contemporary series suggest that renal thermal ablation (including cryoablation or radiofrequency ablation), when selectively employed, can maintain oncologic efficacy comparable to extirpation while minimizing complications and treatment morbidity. Therefore, as the incidence of small renal masses in elderly comorbid patients rises, it is likely we will see ablative techniques assume a greater role in management.
过去几十年见证了新诊断出的小肾肿瘤数量的稳步增加。虽然这些小肾肿瘤在历史上一直通过手术切除来治疗,但现在许多肿瘤已经可以通过微创治疗方式来治疗,包括热消融或主动监测。当代的研究表明,当选择性地使用时,肾热消融(包括冷冻消融或射频消融)可以保持与切除相当的肿瘤学疗效,同时最大限度地减少并发症和治疗的发病率。因此,随着老年合并症患者中小肾肿瘤的发病率上升,消融技术在治疗中可能会发挥更大的作用。