Social Work Program, Elizabeth City State University, Elizabeth City, North Carolina 27909, USA.
Soc Work Public Health. 2011;26(4):405-16. doi: 10.1080/19371918.2011.579488.
Sickle cell disease is one of the most common genetic blood disorders in the United States that affects 1 in every 375 African Americans. Sickle cell disease is an inherited condition caused by abnormal hemoglobin in the red blood cells. The Human Genome Project has provided valuable insight and extensive research advances in the understanding of the human genome and sickle cell disease. Significant progress in genetic knowledge has led to an increase in the ability for researchers to map and sequence genes for diagnosis, treatment, and prevention of sickle cell disease and other chronic illnesses. This article explores some of the recent knowledge and advances about sickle cell disease and the Human Genome Project.
镰状细胞病是美国最常见的遗传性血液疾病之一，影响每 375 名非裔美国人中的 1 人。镰状细胞病是一种由红细胞中异常血红蛋白引起的遗传性疾病。人类基因组计划为理解人类基因组和镰状细胞病提供了有价值的见解和广泛的研究进展。遗传知识的重大进展导致研究人员在为镰状细胞病和其他慢性疾病进行诊断、治疗和预防而绘制和测序基因的能力方面取得了提高。本文探讨了一些关于镰状细胞病和人类基因组计划的最新知识和进展。
