Departamento de Psicología Básica, Psicobiología y Metodología de las Ciencias del Comportamiento, Facultad de Psicología, Universidad de Salamanca, Salamanca, Spain.
BMC Public Health. 2011 Jun 27;11:504. doi: 10.1186/1471-2458-11-504.
Studies centered on the detection of cognitive impairment and its relationship to cardiovascular risk factors in elderly people have gained special relevance in recent years. Knowledge of the cardiovascular risk factors that may be associated to cognitive impairment could be very useful for introducing treatments in early stages - thereby possibly contributing to improve patient quality of life.The present study explores cognitive performance in people over 65 years of age in Salamanca (Spain), with special emphasis on the identification of early symptoms of cognitive impairment, with the purpose of detecting mild cognitive impairment and of studying the relationships between this clinical situation and cardiovascular risk factors.
METHODS/DESIGN: A longitudinal study is contemplated. The reference population will consist of 420 people over 65 years of age enrolled through randomized sampling stratified by healthcare area, and who previously participated in another study.
a) Sociodemographic variables; b) Cardiovascular risk factors; c) Comorbidity; d) Functional level for daily life activities; and e) Study of higher cognitive functions based on a neuropsychological battery especially adapted to the evaluation of elderly people.
We hope that this study will afford objective information on the representative prevalence of cognitive impairment in the population over 65 years of age in Salamanca. We also hope to obtain data on the relationship between cognitive impairment and cardiovascular risk factors in this specific population group. Based on the results obtained, we also will be able to establish the usefulness of some of the screening tests applied during the study, such as the Mini-Mental State Examination and the 7 Minute Screen test.
ClinicalTrials.gov: NCT01327196.
近年来，以老年人认知障碍及其与心血管危险因素的关系为中心的研究特别受到关注。了解可能与认知障碍相关的心血管危险因素，对于在早期引入治疗方法非常有用，从而可能有助于提高患者的生活质量。本研究探讨了西班牙萨拉曼卡地区 65 岁以上人群的认知表现，特别强调识别认知障碍的早期症状，旨在发现轻度认知障碍，并研究这种临床情况与心血管危险因素之间的关系。
方法/设计：考虑进行一项纵向研究。参考人群将由通过按医疗保健区域分层的随机抽样招募的 420 名 65 岁以上的人组成，这些人之前参加过另一项研究。
a) 社会人口统计学变量；b) 心血管危险因素；c) 合并症；d) 日常生活活动的功能水平；e) 基于专门适用于老年人评估的神经心理学成套测验的高级认知功能研究。
我们希望这项研究能为萨拉曼卡 65 岁以上人群认知障碍的代表性患病率提供客观信息。我们还希望获得该特定人群组认知障碍与心血管危险因素之间关系的数据。根据获得的结果，我们还将能够确定在研究中应用的一些筛选测试的有用性，例如简易精神状态检查和 7 分钟筛查测试。
ClinicalTrials.gov：NCT01327196。
