Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Healey Way, Headington, Oxford, UK.
Eur J Vasc Endovasc Surg. 2011 Nov;42(5):577-84. doi: 10.1016/j.ejvs.2011.04.014. Epub 2011 Jun 25.
Abdominal aortic aneurysm (AAA) repairs, both elective and rupture, are associated with significant blood loss often requiring transfusion. Cell-salvage autotransfusion has been developed to reduce the need for allogeneic blood. We review the literature to delineate the role of cell salvage in reducing allogeneic blood use in open AAA repairs.
A systematic search of the English-language literature was performed using the PubMed, Embase and Cochrane databases up to August 2010.
Twenty-three studies were identified. Whilst some data are conflicting, cell salvage appears to reduce overall use and exposure to allogeneic blood, and reduces length of intensive care unit and hospital stay after elective AAA repairs. There may be additional benefit by combining cell salvage with other blood-conservation techniques. Use of cell salvage in ruptured AAA repairs consistently reduced blood-product requirements.
Cell salvage appears to reduce blood-product use in both elective and rupture AAA repairs. Owing to the heterogeneity in methodology of published data, further study may be required before cell salvage becomes standard practice in open AAA repairs.
腹主动脉瘤（AAA）的修复，包括择期手术和破裂，常伴有大量失血，往往需要输血。细胞回收自体输血的发展旨在减少异体输血的需求。我们回顾文献以明确细胞回收在减少开放性 AAA 修复术异体血使用中的作用。
采用 PubMed、Embase 和 Cochrane 数据库，对截至 2010 年 8 月的英文文献进行系统检索。
共确定了 23 项研究。尽管一些数据存在矛盾，但细胞回收似乎确实可以减少整体异体血的使用和暴露，并减少择期 AAA 修复术后重症监护病房和住院时间。将细胞回收与其他血液保护技术结合使用可能会有额外的益处。在破裂性 AAA 修复中使用细胞回收术可始终降低血液制品的需求。
细胞回收似乎可以减少择期和破裂性 AAA 修复术的血液制品使用。由于发表数据的方法学存在异质性，在细胞回收成为开放性 AAA 修复术的标准操作之前，可能需要进一步的研究。
