癌症临床试验参与者的研究信息知识、感知充分性及理解情况

Research information knowledge, perceived adequacy, and understanding in cancer clinical trial participants.

作者信息

Biedrzycki Barbara A

机构信息

Skip Viragh Center for Pancreas Cancer Clinical Research and Patient Care, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA.

出版信息

Oncol Nurs Forum. 2011 Jul;38(4):E291-6. doi: 10.1188/11.ONF.E291-E296.

DOI:10.1188/11.ONF.E291-E296

PMID:21708524

Abstract

PURPOSE/OBJECTIVES: To describe the adequacy of research information among people with cancer at the time they accept or decline participation in a cancer clinical trial.

DESIGN

Cross-sectional, descriptive.

SETTING

An urban, academic, National Cancer Institute-designated comprehensive cancer center.

SAMPLE

197 patients with advanced gastrointestinal cancer.

METHODS

Mailed survey; self-reported data.

MAIN RESEARCH VARIABLES

Adequacy of research information (actual knowledge, perceived adequacy of information, and perceived understanding), cancer clinical trial participation, and satisfaction with the decision to participate.

FINDINGS

Most respondents (88%) perceived themselves as having adequate information to make an informed decision regarding cancer clinical trial participation. In addition, 35% demonstrated adequate knowledge of basic clinical research.

CONCLUSIONS

Patients decide to accept or decline cancer clinical trials without having adequate knowledge.

IMPLICATIONS FOR NURSING

Nurses have an important role in educating patients regarding cancer clinical trials. The ideal teachable moment may not occur at the time of diagnosis; other less stressful opportunities may present when the patient is more receptive.

摘要

目的/目标：描述癌症患者在接受或拒绝参与癌症临床试验时所获研究信息的充分程度。