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一名患有格雷夫斯病的马来女性的桥本脑病病例。

A case of Hashimoto encephalopathy in a Malay woman with Graves disease.

作者信息

Ngiu Chai Soon, Ibrahim Norlinah M, Yahya Wan Nur Nafisah Wan, Tan Hui Jan, Mustafa Norlaila, Basri Hamidon, Ali Raymond Azman

机构信息

Hospital UKM, Department of Medicine, Jalan Yaacob Latiff, Kuala Lumpur, 56000, Malaysia.

出版信息

BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.01.2009.1501. Epub 2009 Jun 26.

Abstract

Hashimoto encephalopathy (HE) is a poorly recognised steroid-responsive encephalopathy, with prominent neuropsychiatric features. Diagnosis is often difficult due to its heterogeneous clinical presentation, especially since the thyroid status or anti-thyroid antibody titres may not be related to the disease state. Here, the case of a 23-year-old Malay woman with Graves disease who presented with progressive encephalopathy diagnosed as HE is presented. She responded dramatically to high dose intravenous and then oral corticosteroid. A month after the initiation of treatment, she regained full independency.

摘要

桥本脑病(HE)是一种认识不足的类固醇反应性脑病,具有突出的神经精神症状。由于其临床表现多样,诊断往往困难,特别是因为甲状腺状态或抗甲状腺抗体滴度可能与疾病状态无关。本文报告了一例23岁患有格雷夫斯病的马来女性,她因进行性脑病被诊断为HE。她对大剂量静脉注射然后口服皮质类固醇有显著反应。治疗开始一个月后,她恢复了完全独立。

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