Huang Xu, Yu Yang, Zhang Hua, Liu Jie, Sun Yuqian, Chang Manli, Cui Can
Department of Endocrinology and Metabolism, The Second Hospital Affiliated to Harbin Medical University, Harbin, Heilongjiang 150080, P.R. China.
Exp Ther Med. 2014 Aug;8(2):515-518. doi: 10.3892/etm.2014.1761. Epub 2014 Jun 5.
Hashimoto's encephalopathy (HE) is an acute encephalopathy associated with Hashimoto's thyroiditis. The majority of reported cases have been associated with hypothyroidism, while cases with hyperthyroidism are rare. The current study reported on a 56-year old female patient with HE, who was found to have progressively aggregated dysarthria, gait disturbance, somniloquy and delirium. Thyroid function tests revealed that the patient had hyperthyroidism, with high levels of anti-thyroid antibodies. Following treatment with corticosteroids, the neurological/psychiatric symptoms of the patient were relieved quickly. The one-year follow-up investigation indicated that there was no recurrence of the disease, demonstrating that the treatment administered for this rare case was effective.
桥本脑病(HE)是一种与桥本甲状腺炎相关的急性脑病。大多数报道的病例与甲状腺功能减退有关,而甲状腺功能亢进的病例则很少见。本研究报告了一名56岁患有HE的女性患者,该患者出现进行性加重的构音障碍、步态障碍、梦呓和谵妄。甲状腺功能检查显示该患者患有甲状腺功能亢进,抗甲状腺抗体水平较高。使用皮质类固醇治疗后,患者的神经/精神症状迅速缓解。一年的随访调查表明该病没有复发,证明针对这一罕见病例的治疗是有效的。