Shahzad Rafia, Younas Farhana
Department of Radiology, Sharif Medical City Hospital, Johar Town, Lahore.
J Coll Physicians Surg Pak. 2011 Jun;21(6):325-9.
To compare magnetic resonance angiography (MRA) with Intra-arterial digital subtraction angiography (IA-DSA) in detection and characterization of intracranial aneurysms.
Comparative cross-sectional study.
Department of Diagnostic Imaging, Lahore General Hospital, Lahore, from January to June 2007.
Thirty patients presented with aneurysmal subarachnoid haemorrhage (SAH) and focal neurological signs were selected by convenience sampling. Three dimensional time of flight (3D TOF) MRA using maximum intensity projection (MIP) was performed on all patients along with DSA. Results of 3D TOF MRA were compared with those of IA-DSA taking IA-DSA as Gold standard.
Out of 30 patients 14 (46.7%) were males and 16 (53.3%) were females with mean age of 41±14.1 years. MRA detected 29 out of 30 aneurysmal lesions with sensitivity of 96.7%. Regarding characterization of aneurysms results of MRA were comparable to those of IA-DSA.
3D TOF MRA technique showed a high sensitivity in this study. This technique can be used as a non-invasive screening test for intracranial aneurysms and as a suitable alternative primary examination to IA-DSA prior to aneurysmal surgery.
比较磁共振血管造影（MRA）与动脉内数字减影血管造影（IA-DSA）在颅内动脉瘤检测及特征描述方面的差异。
比较性横断面研究。
2007年1月至6月，拉合尔拉合尔综合医院诊断影像科。
通过便利抽样选取30例出现动脉瘤性蛛网膜下腔出血（SAH）及局灶性神经体征的患者。对所有患者进行三维时间飞跃法（3D TOF）MRA检查，并采用最大密度投影（MIP）技术，同时进行DSA检查。以IA-DSA为金标准，将3D TOF MRA的结果与之进行比较。
30例患者中，男性14例（46.7%），女性16例（53.3%），平均年龄41±14.1岁。MRA在30个动脉瘤性病变中检测出29个，敏感性为96.7%。在动脉瘤特征描述方面，MRA的结果与IA-DSA相当。
本研究中3D TOF MRA技术显示出较高的敏感性。该技术可作为颅内动脉瘤的无创筛查试验，也可作为动脉瘤手术前IA-DSA合适的替代初筛检查。
