Xu Jianda, Zhao Hong, Jiang Tao, Gao Yi, Zheng Chong, Wang Bin, Qu Yuxing
Department of Orthopaedics, Changzhou Traditional Chinese Medical Hospital, Nanjing University of Traditional Chinese Medicine, Changzhou, Jiangsu Province, China.
Neuro Endocrinol Lett. 2011;32(3):234-7.
Granulocytic sarcoma (GS) may be a presenting sign of myelogenous leukemia. Occasionally, an extramedullary neoplasm composed from myelocytic precursor cells occurs in patients without evidence of leukemia. Rarely, undiagnosed leukemia occurs initially manifesting with paralysis to spinal cord GS. We present a case report of 20-year-old girl with an undiagnosed leukemia, initially manifesting as paralysis. En bloc spondylectomy with chemotherapy postoperatively constituted the treatment of choice for this tumor. After two courses of chemotherapy, the patient made a good postoperative recovery with notable bilateral lower extremity improvement.
粒细胞肉瘤(GS)可能是骨髓性白血病的首发症状。偶尔,骨髓细胞前体细胞组成的髓外肿瘤会出现在无白血病证据的患者中。罕见的是,未确诊的白血病最初表现为脊髓GS导致的瘫痪。我们报告一例20岁女孩的病例,她患有未确诊的白血病,最初表现为瘫痪。整块脊椎切除术联合术后化疗是该肿瘤的首选治疗方法。经过两个疗程的化疗,患者术后恢复良好,双侧下肢有明显改善。