Dhurat Rachita P, Deshpande Deepal J
Department of Dermatology, TNMC and BYL Nair Charitable Hospital, Mumbai Central, Mumbai-400 008, India.
Int J Trichology. 2010 Jul;2(2):96-100. doi: 10.4103/0974-7753.77513.
Loose anagen syndrome (LAS) is a benign, self-limiting condition where anagen hairs are easily and painlessly extracted. It is mainly reported in childhood; however, it may variably present in adulthood as well. The presence of anagen hair devoid of its sheath and with 'floppy sock appearance' is a characteristic feature of loose anagen hair (LAH) on trichogram. LAH can be seen in normal population and in alopecia areata. The percentage of LAH in LAS is more than 50%. The histopathological findings show clefting between the layers of hair and are very useful in differentiating LAS from alopecia areata. Here, a review on the diagnostic criteria and practical guidelines are discussed so as to enable the trichologist in managing this benign, self-limiting condition and differentiating it from the other causes of non-scarring alopecias.
生长期松动综合征（LAS）是一种良性的、自限性疾病，其中生长期毛发很容易且无痛地被拔出。它主要在儿童期被报道；然而，在成年期也可能有不同表现。生长期毛发缺乏毛鞘且呈“松软短袜外观”是毛发显微镜检查中生长期松动毛发（LAH）的特征性表现。LAH可见于正常人群和斑秃患者。LAS中LAH的比例超过50%。组织病理学检查结果显示毛发各层之间有裂隙，这对于将LAS与斑秃区分开来非常有用。在此，对诊断标准和实用指南进行综述，以便毛发学家能够处理这种良性的、自限性疾病，并将其与其他非瘢痕性脱发的原因区分开来。
