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印度痰液标本中分离出蒙纳分枝杆菌的首次报告。

First report on isolation of Mycobacterium monacense from sputum specimen in India.

作者信息

Therese K Lily, Gayathri R, Thiruppathi K, Madhavan H N

机构信息

L & T Microbiology Research Centre, Vision Research Foundation, Chennai, India.

出版信息

Lung India. 2011 Apr;28(2):124-6. doi: 10.4103/0970-2113.80326.

DOI:10.4103/0970-2113.80326
PMID:21712923
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3109835/
Abstract

We report a case of Mycobacterium monacense (M. monacense) isolated from sputum of a female patient for the first time in India. The chest radiograph and symptoms were suggestive of pulmonary tuberculosis. M. monacense was isolated from the sputum specimen at the end of 11 days of incubation. The identification was confirmed by conventional biochemical tests and polymerase chain reaction (PCR) -based Restriction Fragment Length Polymorphism (RFLP) and DNA sequencing targeting Internal Transcribed Spacer (ITS) region and hsp65 gene. The patient was treated with conventional anti-tuberculous drugs.

摘要

我们首次在印度报道了一例从一名女性患者痰液中分离出蒙氏分枝杆菌的病例。胸部X光片和症状提示为肺结核。在培养11天后从痰液标本中分离出蒙氏分枝杆菌。通过传统生化试验以及基于聚合酶链反应（PCR）的限制性片段长度多态性分析（RFLP）和针对内转录间隔区（ITS）和hsp65基因的DNA测序来确认鉴定结果。该患者接受了传统抗结核药物治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a13/3109835/dc35a3d87e71/LI-28-124-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a13/3109835/f96ff3cfe225/LI-28-124-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a13/3109835/f05eae7ab191/LI-28-124-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a13/3109835/dc35a3d87e71/LI-28-124-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a13/3109835/f96ff3cfe225/LI-28-124-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a13/3109835/f05eae7ab191/LI-28-124-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a13/3109835/dc35a3d87e71/LI-28-124-g003.jpg

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本文引用的文献

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Mycobacterium monacense in a patient with a pulmonary tumor.一名患有肺部肿瘤患者体内的蒙纳分枝杆菌。
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Ocular infections due to non-tuberculous mycobacteria.
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New Microbes New Infect. 2016 Jan 22;10:112-5. doi: 10.1016/j.nmni.2016.01.006. eCollection 2016 Mar.
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Clin Microbiol Rev. 2014 Oct;27(4):727-52. doi: 10.1128/CMR.00035-14.
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非结核分枝杆菌所致眼部感染
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