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术前移植患者进行常规鼻窦CT扫描的可行性。

Feasibility of routine paranasal sinus CT-scans in preoperative transplant patients.

作者信息

Tomazic Peter, Neuschitzer Andreas, Koele Wolfgang, Lang-Loidolt Doris

机构信息

ENT-University Hospital, Medical University Graz, Austria.

出版信息

Ann Transplant. 2011 Apr-Jun;16(2):31-5. doi: 10.12659/aot.881862.

Abstract

BACKGROUND

Paranasal Sinus (PNS) CT- scans are routinely performed for screening of sinusitis in patients scheduled for organ transplant at the University Hospital Graz. This study was performed to evaluate whether routine PNS CT-scans are necessary in every transplant patient or in selected cases only, because clear evidence is missing in literature.

MATERIAL/METHODS: 142 patients (113 male, 29 female) were included in this retrospective patient chart study.

RESULTS

The majority of patients (n=142) were scheduled for liver transplant (n=79). Of all patients (n=142), 50 (35.2%) had normal PNS CT-scans and 92 (64.8%) had a pathologically changed PNS-scan. Seventy-one out of these 92 (77.2%) patients did not show clinical symptoms of sinusitis nor changes in diagnostic endoscopy, 21 (22.8%) patients did have symptoms of sinusitis and diseased PNS CT-scans. Three out of 71 (4.2%) without symptoms but pathologic CT-scans compared to 7/21 (33.3%) patients with symptoms and pathological CT-scans underwent endoscopic paranasal sinus surgery (FESS). All patients operated suffered from chronic sinusitis, none had mycotic or neoplastic disease in definite histology.

CONCLUSIONS

Since there was a high rate (77.2%) of pathological CT scans unrelated to sinusitis symptoms these findings should be considered as accidental. In our opinion routine paranasal sinus CT scans are not feasible in patients scheduled for organ transplant according to high rate of false positive results.

摘要

背景

格拉茨大学医院对计划进行器官移植的患者常规进行鼻窦(PNS)CT扫描以筛查鼻窦炎。由于文献中缺乏明确证据,本研究旨在评估常规PNS CT扫描是对每位移植患者都必要还是仅在特定病例中必要。

材料/方法:本回顾性病历研究纳入了142例患者(男113例,女29例)。

结果

大多数患者(n = 142)计划进行肝移植(n = 79)。在所有患者(n = 142)中,50例(35.2%)PNS CT扫描正常,92例(64.8%)PNS扫描有病理改变。这92例患者中有71例(77.2%)既没有鼻窦炎的临床症状,诊断性鼻内镜检查也没有变化,21例(22.8%)患者有鼻窦炎症状且PNS CT扫描异常。71例无症状但CT扫描异常的患者中有3例(4.2%)与21例有症状且CT扫描异常的患者中的7例(33.3%)接受了鼻内镜鼻窦手术(FESS)。所有接受手术的患者均患有慢性鼻窦炎,组织学确诊均无真菌或肿瘤性疾病。

结论

由于与鼻窦炎症状无关的病理CT扫描率较高(77.2%),这些发现应被视为偶然情况。我们认为,鉴于假阳性率较高,常规鼻窦CT扫描对计划进行器官移植的患者不可行。

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