Correlation between Reid's colposcopic index and histologic results from colposcopically directed biopsy in differentiating high-grade from low-grade squamous intraepithelial lesion at Rajavithi Hospital.

OBJECTIVE

To analyze the correlation and accuracy between Reid's colposcopic index (RCI) and histologic results from colposcopically directed biopsy (CDB) in differentiating high-grade squamous intraepithelial lesion (HSIL) from low-grade squamous intraepithelial lesion (LSIL).

MATERIALS AND METHOD

A retrospective analysis of medical records of women who had abnormal Pap smear and underwent colposcopy, RCI scoring and CDB from January 1st, 2003 to December 31st, 2006 at Rajavithi Hospital was conducted.

RESULTS

One hundred women were included in the present study. Compared with histological diagnosis from CDB, accuracy for four colposcopic criteria: margin pattern, color, vascular pattern and iodiness staining were 73.0%, 79.0%, 75.0% and 69.2%, respectively. Combining these variables into RCI showed 89.0% overall accuracy. Color and vascular pattern showed a good agreement with histologic results from CDB (Kendall's tau C = 0.68 and 0.63; p < 0.05). Overall, RCI yielded a good agreement (Kendall's tau C = 0.66; p < 0.05).

CONCLUSION

RCI yields a good correlation with histology from CDB and it has high accuracy in differentiating HSIL from LSIL.