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在拉贾维蒂医院,里德阴道镜指数与阴道镜引导下活检的组织学结果在鉴别高级别与低级别鳞状上皮内病变中的相关性。

Correlation between Reid's colposcopic index and histologic results from colposcopically directed biopsy in differentiating high-grade from low-grade squamous intraepithelial lesion at Rajavithi Hospital.

作者信息

Boonlikit Sathone

机构信息

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2011 Mar;94 Suppl 2:S59-65.

PMID:21717880
Abstract

OBJECTIVE

To analyze the correlation and accuracy between Reid's colposcopic index (RCI) and histologic results from colposcopically directed biopsy (CDB) in differentiating high-grade squamous intraepithelial lesion (HSIL) from low-grade squamous intraepithelial lesion (LSIL).

MATERIALS AND METHOD

A retrospective analysis of medical records of women who had abnormal Pap smear and underwent colposcopy, RCI scoring and CDB from January 1st, 2003 to December 31st, 2006 at Rajavithi Hospital was conducted.

RESULTS

One hundred women were included in the present study. Compared with histological diagnosis from CDB, accuracy for four colposcopic criteria: margin pattern, color, vascular pattern and iodiness staining were 73.0%, 79.0%, 75.0% and 69.2%, respectively. Combining these variables into RCI showed 89.0% overall accuracy. Color and vascular pattern showed a good agreement with histologic results from CDB (Kendall's tau C = 0.68 and 0.63; p < 0.05). Overall, RCI yielded a good agreement (Kendall's tau C = 0.66; p < 0.05).

CONCLUSION

RCI yields a good correlation with histology from CDB and it has high accuracy in differentiating HSIL from LSIL.

摘要

目的

分析在鉴别高级别鳞状上皮内病变(HSIL)与低级别鳞状上皮内病变(LSIL)时,Reid阴道镜指数(RCI)与阴道镜引导下活检(CDB)组织学结果之间的相关性及准确性。

材料与方法

对2003年1月1日至2006年12月31日在拉贾维蒂医院进行宫颈涂片异常并接受阴道镜检查、RCI评分及CDB的女性病历进行回顾性分析。

结果

本研究纳入100名女性。与CDB的组织学诊断相比,四种阴道镜标准(边缘形态、颜色、血管形态及碘染色)的准确率分别为73.0%、79.0%、75.0%和69.2%。将这些变量合并为RCI后总体准确率为89.0%。颜色和血管形态与CDB的组织学结果具有良好的一致性(肯德尔tau C系数分别为0.68和0.63;p<0.05)。总体而言,RCI具有良好的一致性(肯德尔tau C系数为0.66;p<0.05)。

结论

RCI与CDB的组织学结果具有良好的相关性,在鉴别HSIL与LSIL方面具有较高的准确性。

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