Radiation Medicine Centre (Bhabha Atomic Research Centre), Tata Memorial Hospital Annexe, Bombay, India.
Ann N Y Acad Sci. 2011 Jun;1228:1-18. doi: 10.1111/j.1749-6632.2011.06077.x.
In this review, the fundamental principles of fluorodeoxyglucose (FDG) positron emission tomography (PET) and FDG PET/computed tomography (CT) imaging have been described. The basic physics of PET instrumentation, radiotracer chemistry, and the artifacts, as well as normal physiological or benign pathological variants, have been described and presented to the readers in a lucid manner to enable them an easy grasp of the fundamentals of the subject. Finally, we have outlined the current developments in quantitative PET imaging, including dual time point and delayed PET imaging, time-of-flight technology in PET imaging and partial volume correction, and global disease assessment with their potential of being incorporated into the assessment of benign and malignant disorders.
在这篇综述中，描述了氟代脱氧葡萄糖（FDG）正电子发射断层扫描（PET）和 FDG PET/计算机断层扫描（CT）成像的基本原理。以通俗易懂的方式向读者描述了 PET 仪器仪表、放射性示踪剂化学、伪影以及正常的生理或良性病理变异，使他们能够轻松掌握该主题的基础知识。最后，我们概述了定量 PET 成像的当前发展，包括双时间点和延迟 PET 成像、PET 成像中的飞行时间技术和部分容积校正，以及使用它们对良性和恶性疾病进行整体疾病评估的潜力。
